B0009821 Microglial cell, mouse hippocampus
Credit: Simon Beggs. Wellcome Images
Confocal micrograph of a microglial cell in the hippocampus region of a mouse brain. Here a single microglia (red and green) can be seen straddling the entire hippocampal pyramidal layer (blue), with its numerous filamentous processes extending out and contacting many individual neurones. Microglial cells were long thought to simply be the immune cell of the central nervous system (CNS). It is now clear that they have many other functions including regulating and directing the activity of neurons throughout development and into adulthood, and even controlling whether neurons survive or die. Width of image is 60 micrometres.
2014 Published: –
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